1 keywords

CATH Domain 4kqeA04

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.800 Anticodon-binding domain

Domain Context

CATH Clusters

Superfamily Anticodon-binding domain
Functional Family Glycine--tRNA ligase 2

Enzyme Information

2.7.7.-
Nucleotidyltransferases.
based on mapping to UniProt P41250
6.1.1.14
Glycine--tRNA ligase.
based on mapping to UniProt P41250
ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

UniProtKB Entries (1)

P41250
GARS_HUMAN
Homo sapiens
Glycine--tRNA ligase

PDB Structure

PDB 4KQE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis
Deng, X., Qin, X., Chen, L., Jia, Q., Zhang, Y., Zhang, Z., Lei, D., Ren, G., Zhou, Z., Wang, Z., Li, Q., Xie, W.
J.Biol.Chem.