CATH Classification

Domain Context

CATH Clusters

Superfamily Alkaline Phosphatase, subunit A
Functional Family Alkaline phosphatase

Enzyme Information

3.1.3.1
Alkaline phosphatase.
based on mapping to UniProt P15693
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Active at a high pH optimum. -!- Wide specificity. -!- Also catalyzes transphosphorylations. -!- Some enzymes hydrolyze diphosphate (cf. EC 3.6.1.1).

UniProtKB Entries (1)

P15693
PPBI1_RAT
Rattus norvegicus
Intestinal-type alkaline phosphatase 1

PDB Structure

PDB 4KJD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of rat intestinal alkaline phosphatase - Role of crown domain in mammalian alkaline phosphatases.
Ghosh, K., Mazumder Tagore, D., Anumula, R., Lakshmaiah, B., Kumar, P.P., Singaram, S., Matan, T., Kallipatti, S., Selvam, S., Krishnamurthy, P., Ramarao, M.
J.Struct.Biol.