CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1280.300
Functional Family

Enzyme Information

3.1.11.-
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q38087
2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q38087
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q38087
DPOL_BPR69
Enterobacteria phage RB69
DNA-directed DNA polymerase

PDB Structure

PDB 4KHQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-function analysis of ribonucleotide bypass by B family DNA replicases.
Clausen, A.R., Murray, M.S., Passer, A.R., Pedersen, L.C., Kunkel, T.A.
Proc.Natl.Acad.Sci.USA