CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P10584
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

P10584
MDH_THETH
Thermus thermophilus
Malate dehydrogenase

PDB Structure

PDB 4KDF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures and molecular dynamics simulations of thermophilic malate dehydrogenase reveal critical loop motion for co-substrate binding.
Hung, C.H., Hwang, T.S., Chang, Y.Y., Luo, H.R., Wu, S.P., Hsu, C.H.
Plos One