CATH Classification

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P10844
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (2)

P46097
SYT2_MOUSE
Mus musculus
Synaptotagmin-2
P10844
BXB_CLOBO
Clostridium botulinum
Botulinum neurotoxin type B

PDB Structure

PDB 4KBB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of dual receptor binding to botulinum neurotoxin B.
Berntsson, R.P., Peng, L., Dong, M., Stenmark, P.
Nat Commun