CATH Classification

Domain Context

CATH Clusters

Superfamily
Functional Family -

PDB Structure

PDB 4JTZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular Dynamics Simulations and Structure-Based Rational Design Lead to Allosteric HCV NS5B Polymerase Thumb Pocket 2 Inhibitor with Picomolar Cellular Replicon Potency.
Hucke, O., Coulombe, R., Bonneau, P., Bertrand-Laperle, M., Brochu, C., Gillard, J., Joly, M.A., Landry, S., Lepage, O., Llinas-Brunet, M., Pesant, M., Poirier, M., Poirier, M., McKercher, G., Marquis, M., Kukolj, G., Beaulieu, P.L., Stammers, T.A.
J.Med.Chem.