CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1480 | sialyltransferase cstii, chain A |
|
3.90.1480.20 | Glycosyl transferase family 29 |
Domain Context
CATH Clusters
| Superfamily | Glycosyl transferase family 29 |
| Functional Family | ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
Enzyme Information
| 2.4.99.1 |
Beta-galactoside alpha-(2,6)-sialyltransferase.
based on mapping to UniProt P15907
CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-R = CMP + N-acetyl- alpha-neuraminyl-(2->6)-beta-D-galactosyl-R.
-!- The enzyme acts on the terminal non-reducing beta-D-galactosyl residue of the oligosaccharide moiety of glycoproteins and glycolipids. -!- Formerly EC 2.4.99.11.
|
UniProtKB Entries (1)
| P15907 |
SIAT1_HUMAN
Homo sapiens
Beta-galactoside alpha-2,6-sialyltransferase 1
|
PDB Structure
| PDB | 4JS1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structure of human alpha-2,6-sialyltransferase reveals the binding mode of complex glycans.
Acta Crystallogr.,Sect.D
|