CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family Succinylornithine transaminase

Enzyme Information

2.6.1.11
Acetylornithine transaminase.
based on mapping to UniProt P40732
N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
-!- Also acts on L-ornithine and N(2)-succinyl-L-ornithine.
2.6.1.17
Succinyldiaminopimelate transaminase.
based on mapping to UniProt P40732
N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2- L-amino-6-oxoheptanedioate + L-glutamate.

UniProtKB Entries (1)

P40732
ARGD_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Acetylornithine/succinyldiaminopimelate aminotransferase

PDB Structure

PDB 4JEY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases
Bisht, S., Bharath, S.R., Murthy, M.R.N.
To be Published