CATH Domain 4jbsA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1730	tricorn interacting facor f3 domain

Domain Context

CATH Clusters

Superfamily	tricorn interacting facor f3 domain
Functional Family	Endoplasmic reticulum aminopeptidase 2

Enzyme Information

3.4.11.-

Aminopeptidases.

based on mapping to UniProt Q6P179

UniProtKB Entries (1)

ERAP2_HUMAN

Homo sapiens

Endoplasmic reticulum aminopeptidase 2

PDB Structure

PDB	4JBS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses. Zervoudi, E., Saridakis, E., Birtley, J.R., Seregin, S.S., Reeves, E., Kokkala, P., Aldhamen, Y.A., Amalfitano, A., Mavridis, I.M., James, E., Georgiadis, D., Stratikos, E. Proc.Natl.Acad.Sci.USA