CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.47.10
Functional Family

Enzyme Information

UniProtKB Entries (1)

O54440
O54440_PSEAI
Pseudomonas aeruginosa
3-oxoacyl-[acyl-carrier-protein] synthase 2

PDB Structure

PDB 4JB6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of Pseudomonas aeruginosa beta-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the crystal form.
Baum, B., Lecker, L.S., Zoltner, M., Jaenicke, E., Schnell, R., Hunter, W.N., Brenk, R.
Acta Crystallogr F Struct Biol Commun