CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome P450-Terp, domain 2
Functional Family Citrate synthase

Enzyme Information

2.3.3.16
Citrate synthase (unknown stereospecificity).
based on mapping to UniProt P0ABH7
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
-!- This entry has been included to accommodate those citrate synthases for which the stereospecificity with respect to C(2) of oxaloacetate has not been established (cf. EC 2.3.3.1 and EC 2.3.3.3).

UniProtKB Entries (1)

P0ABH7
CISY_ECOLI
Escherichia coli K-12
Citrate synthase

PDB Structure

PDB 4JAE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Enzyme-substrate complexes of allosteric citrate synthase: Evidence for a novel intermediate in substrate binding.
Duckworth, H.W., Nguyen, N.T., Gao, Y., Donald, L.J., Maurus, R., Ayed, A., Bruneau, B., Brayer, G.D.
Biochim.Biophys.Acta