CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.140.80
Functional Family

Enzyme Information

3.6.1.54
UDP-2,3-diacylglucosamine diphosphatase.
based on mapping to UniProt A0A0H3C8Q1
UDP-2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosamine + H(2)O = 2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosaminyl 1-phosphate + UMP.
-!- The enzyme catalyzes a step in the biosynthesis of lipid A. -!- Formerly EC 3.6.1.n5.

UniProtKB Entries (1)

A0A0H3C8Q1
A0A0H3C8Q1_CAUVN
Caulobacter vibrioides NA1000
UDP-2,3-diacylglucosamine pyrophosphatase LpxI

PDB Structure

PDB 4J6E
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
LpxI structures reveal how a lipid A precursor is synthesized.
Metzger IV, L.E., Lee, J.K., Finer-Moore, J.S., Raetz, C.R.H., Stroud, R.M.
Nat.Struct.Mol.Biol.