CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Enoyl-[acyl-carrier-protein] reductase [NADH] |
Enzyme Information
UniProtKB Entries (1)
| Q5NGQ3 |
Q5NGQ3_FRATT
Francisella tularensis subsp. tularensis SCHU S4
Enoyl-[acyl-carrier-protein] reductase [NADH]
|
PDB Structure
| PDB | 4J1N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI).
Bioorg.Med.Chem.Lett.
|