CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q13546
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q13546
RIPK1_HUMAN
Homo sapiens
Receptor-interacting serine/threonine-protein kinase 1

PDB Structure

PDB 4ITH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of RIP1 Inhibition by Necrostatins.
Xie, T., Peng, W., Liu, Y., Yan, C., Maki, J., Degterev, A., Yuan, J., Shi, Y.
Structure