CATH Classification

Domain Context

CATH Clusters

Superfamily Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family Friend leukemia integration 1 transcription factor

Enzyme Information

UniProtKB Entries (1)

P11308
ERG_HUMAN
Homo sapiens
Transcriptional regulator ERG

PDB Structure

PDB 4IRH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Regan, M.C., Horanyi, P.S., Pryor, E.E., Sarver, J.L., Cafiso, D.S., Bushweller, J.H.
Proc.Natl.Acad.Sci.USA