CATH Domain 4ir6A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain adjacent to zinc finger domain protein 2B

Enzyme Information

UniProtKB Entries (1)

BAZ2B_HUMAN

Homo sapiens

Bromodomain adjacent to zinc finger domain protein 2B

PDB Structure

PDB	4IR6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B. Chen, P., Chaikuad, A., Bamborough, P., Bantscheff, M., Bountra, C., Chung, C.W., Fedorov, O., Grandi, P., Jung, D., Lesniak, R., Lindon, M., Muller, S., Philpott, M., Prinjha, R., Rogers, C., Selenski, C., Tallant, C., Werner, T., Willson, T.M., Knapp, S., Drewry, D.H. J.Med.Chem.