CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family probable histone-lysine N-methyltransferase PRDM7

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9NQV7
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q9NQV7
PRDM9_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase PRDM9

PDB Structure

PDB 4IJD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of methyltransferase domain of human PR domain-containing protein 9
Dombrovski, L., Dong, A., Li, Y., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Wu, H., Structural Genomics Consortium (SGC)
To be Published