CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.190.80
Functional Family Fructose-1,6-bisphosphatase class 1

Enzyme Information

3.1.3.11
Fructose-bisphosphatase.
based on mapping to UniProt O00757
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

UniProtKB Entries (1)

O00757
F16P2_HUMAN
Homo sapiens
Fructose-1,6-bisphosphatase isozyme 2

PDB Structure

PDB 4HE0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Shi, R., Chen, Z.Y., Zhu, D.W., Li, C., Shan, Y., Xu, G., Lin, S.X.
Plos One