CATH Domain 4hd0A02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.110	Translation Initiation Factor IF3
	3.30.110.80	DNA double-strand break repair nuclease

Domain Context

CATH Clusters

Superfamily	DNA double-strand break repair nuclease
Functional Family

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt Q8U1N9

UniProtKB Entries (1)

MRE11_PYRFU

Pyrococcus furiosus DSM 3638

DNA double-strand break repair protein Mre11

PDB Structure

PDB	4HD0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair. Limbo, O., Moiani, D., Kertokalio, A., Wyman, C., Tainer, J.A., Russell, P. Nucleic Acids Res.