CATH Classification

Domain Context

CATH Clusters

Superfamily DNA double-strand break repair nuclease
Functional Family

Enzyme Information

3.1.-.-
Acting on ester bonds.
based on mapping to UniProt Q8U1N9

UniProtKB Entries (1)

Q8U1N9
MRE11_PYRFU
Pyrococcus furiosus DSM 3638
DNA double-strand break repair protein Mre11

PDB Structure

PDB 4HD0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
Limbo, O., Moiani, D., Kertokalio, A., Wyman, C., Tainer, J.A., Russell, P.
Nucleic Acids Res.