CATH Classification

Domain Context

CATH Clusters

Superfamily Carbon-nitrogen hydrolase
Functional Family Deaminated glutathione amidase

Enzyme Information

3.5.1.128
Deaminated glutathione amidase.
based on mapping to UniProt P47016
N-(4-oxoglutaryl)-L-cysteinylglycine + H(2)O = 2-oxoglutarate + L-cysteinylglycine.
-!- The enzyme, present in animals, fungi and bacteria, is involved in clearing cells of the toxic compound deaminated glutathione, which can be produced as an unwanted side product by several transaminases.

UniProtKB Entries (1)

P47016
NIT2_YEAST
Saccharomyces cerevisiae S288C
Deaminated glutathione amidase

PDB Structure

PDB 4H5U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Liu, H., Gao, Y., Zhang, M., Qiu, X., Cooper, A.J.L., Niu, L., Teng, M.
Acta Crystallogr.,Sect.D