CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.110 | Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase |
|
3.60.110.10 | Carbon-nitrogen hydrolase |
Domain Context
CATH Clusters
| Superfamily | Carbon-nitrogen hydrolase |
| Functional Family |
Enzyme Information
| 3.5.1.4 |
Amidase.
based on mapping to UniProt Q9L543
A monocarboxylic acid amide + H(2)O = a monocarboxylate + NH(3).
|
UniProtKB Entries (1)
| Q9L543 |
AMIE_BACSP
Bacillus sp. (in: Bacteria)
Aliphatic amidase
|
PDB Structure
| PDB | 4GYN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning.
J.Biol.Chem.
|