CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Tyrosine-protein phosphatase non-receptor type 12

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q99952
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q99952
PTN18_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 18

PDB Structure

PDB 4GFU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
PTPN18-HER2 peptides
Wang, H.M., Yang, F., Du, Y.J., Yang, D.X., Zhang, Y., Yu, X., Sun, J.P.
To be Published