CATH Domain 4g8oA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.497	Antithrombin; Chain I, domain 2
	3.30.497.10	Antithrombin, subunit I, domain 2

Domain Context

CATH Clusters

Superfamily	Antithrombin, subunit I, domain 2
Functional Family	Plasminogen activator inhibitor 1

Enzyme Information

UniProtKB Entries (1)

PAI1_HUMAN

Homo sapiens

Plasminogen activator inhibitor 1

PDB Structure

PDB	4G8O
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Li, S.H., Reinke, A.A., Sanders, K.L., Emal, C.D., Whisstock, J.C., Stuckey, J.A., Lawrence, D.A. Proc.Natl.Acad.Sci.USA