CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9Y6M4
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q9Y6M4
KC1G3_HUMAN
Homo sapiens
Casein kinase I isoform gamma-3

PDB Structure

PDB 4G17
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1g)inhibitors
Hua, Z., Huang, X., Bregman, H., Chakka, N., DiMauro, E.F., Doherty, E.M., Goldstein, J., Gunaydin, H., Huang, H., Mercede, S., Newcomb, J., Patel, V.F., Turci, S.M., Yan, J., Wilson, C., Martin, M.W.
Bioorg.Med.Chem.Lett.