CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.550 | Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A |
|
3.90.550.60 |
Domain Context
CATH Clusters
| Superfamily | 3.90.550.60 |
| Functional Family | UDP-galactofuranosyl transferase GlfT2 |
Enzyme Information
| 2.4.1.288 |
Galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho- decaprenol beta-1,5/1,6-galactofuranosyltransferase.
based on mapping to UniProt O53585
28 UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D- galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D- glucosaminyl-diphospho-trans,octacis-decaprenol = 28 UDP + (beta-D- galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6))(14)-beta-D- galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L- rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho- trans,octacis-decaprenol.
-!- Isolated from Mycobacterium tuberculosis. -!- The enzyme adds approximately twenty-eight galactofuranosyl residues with alternating 1->5 and 1->6 links forming a galactan domain with approximately thirty galactofuranosyl residues. -!- Involved in the formation of the cell wall in mycobacteria.
|
UniProtKB Entries (1)
| O53585 |
GLFT2_MYCTU
Mycobacterium tuberculosis H37Rv
Galactofuranosyltransferase GlfT2
|
PDB Structure
| PDB | 4FIY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Tetrameric Structure of the GlfT2 Galactofuranosyltransferase Reveals a Scaffold for the Assembly of Mycobacterial Arabinogalactan.
J.Biol.Chem.
|