CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Non-specific serine/threonine protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O96013
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O96013
PAK4_HUMAN
Homo sapiens
Serine/threonine-protein kinase PAK 4

PDB Structure

PDB 4FIH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate.
Ha, B.H., Davis, M.J., Chen, C., Lou, H.J., Gao, J., Zhang, R., Krauthammer, M., Halaban, R., Schlessinger, J., Turk, B.E., Boggon, T.J.
Proc.Natl.Acad.Sci.USA