1 keywords

CATH Domain 4feeA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1220 TPP-binding domain

Domain Context

CATH Clusters

Superfamily TPP-binding domain
Functional Family Pyruvate oxidase

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 4FEE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Unexpected tautomeric equilibria of the carbanion-enamine intermediate in pyruvate oxidase highlight unrecognized chemical versatility of thiamin.
Meyer, D., Neumann, P., Koers, E., Sjuts, H., Ludtke, S., Sheldrick, G.M., Ficner, R., Tittmann, K.
Proc.Natl.Acad.Sci.USA