CATH Classification

Domain Context

CATH Clusters

Superfamily SIR2/SIRT2 'Small Domain'
Functional Family NAD-dependent protein deacylase sirtuin-5, mitochondrial

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q9NXA8

UniProtKB Entries (1)

Q9NXA8
SIR5_HUMAN
Homo sapiens
NAD-dependent protein deacylase sirtuin-5, mitochondrial

PDB Structure

PDB 4F56
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Bicyclic Intermediate Structure Provides Insights into the Desuccinylation Mechanism of Human Sirtuin 5 (SIRT5)
Zhou, Y., Zhang, H., He, B., Du, J., Lin, H., Cerione, R.A., Hao, Q.
J.Biol.Chem.