CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Probable serine/threonine-protein kinase roco4

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q6XHB2
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q6XHB2
ROCO4_DICDI
Dictyostelium discoideum
Probable serine/threonine-protein kinase roco4

PDB Structure

PDB 4F1M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations.
Gilsbach, B.K., Ho, F.Y., Vetter, I.R., van Haastert, P.J., Wittinghofer, A., Kortholt, A.
Proc.Natl.Acad.Sci.USA