CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1280.180
Functional Family Carnitine O-palmitoyltransferase 2, mitochondrial

Enzyme Information

2.3.1.21
Carnitine O-palmitoyltransferase.
based on mapping to UniProt P18886
Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.
-!- Broad specificity to acyl group, over the range C(8) to C(18); optimal activity with palmitoyl-CoA (cf. EC 2.3.1.7 and EC 2.3.1.137).

UniProtKB Entries (1)

P18886
CPT2_RAT
Rattus norvegicus
Carnitine O-palmitoyltransferase 2, mitochondrial

PDB Structure

PDB 4EYW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Isothermal titration calorimetry with micelles: Thermodynamics of inhibitor binding to carnitine palmitoyltransferase 2 membrane protein.
Perspicace, S., Rufer, A.C., Thoma, R., Mueller, F., Hennig, M., Ceccarelli, S., Schulz-Gasch, T., Seelig, J.
FEBS Open Bio