CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.7
Acetylcholinesterase.
based on mapping to UniProt P22303
Acetylcholine + H(2)O = choline + acetate.
-!- Acts on a variety of acetic esters. -!- Also catalyzes transacetylations.

UniProtKB Entries (1)

P22303
ACES_HUMAN
Homo sapiens
Acetylcholinesterase

PDB Structure

PDB 4EY5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of human acetylcholinesterase in complex with pharmacologically important ligands.
Cheung, J., Rudolph, M.J., Burshteyn, F., Cassidy, M.S., Gary, E.N., Love, J., Franklin, M.C., Height, J.J.
J.Med.Chem.