CATH Classification

Domain Context

CATH Clusters

Superfamily Udp N-acetylglucosamine O-acyltransferase, C-terminal domain
Functional Family

Enzyme Information

2.3.1.129
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase.
based on mapping to UniProt Q2SWY6
(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetyl-alpha-D- glucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)- N-acetyl-alpha-D-glucosamine.
-!- Involved with EC 2.4.1.182 and EC 2.7.1.130 in the biosynthesis of the phosphorylated glycolipid, lipid A, in the outer membrane of Escherichia coli.

UniProtKB Entries (1)

Q2SWY6
LPXA_BURTA
Burkholderia thailandensis E264
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

PDB Structure

PDB 4EQY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Combining functional and structural genomics to sample the essential Burkholderia structome.
Baugh, L., Gallagher, L.A., Patrapuvich, R., Clifton, M.C., Gardberg, A.S., Edwards, T.E., Armour, B., Begley, D.W., Dieterich, S.H., Dranow, D.M., Abendroth, J., Fairman, J.W., Fox, D., Staker, B.L., Phan, I., Gillespie, A., Choi, R., Nakazawa-Hewitt, S., Nguyen, M.T., Napuli, A., Barrett, L., Buchko, G.W., Stacy, R., Myler, P.J., Stewart, L.J., Manoil, C., Van Voorhis, W.C.
Plos One