CATH Classification

Domain Context

CATH Clusters

Superfamily Histidine kinase-like ATPase, C-terminal domain
Functional Family DNA gyrase subunit B

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 4EMV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV.
Manchester, J.I., Dussault, D.D., Rose, J.A., Boriack-Sjodin, P.A., Uria-Nickelsen, M., Ioannidis, G., Bist, S., Fleming, P., Hull, K.G.
Bioorg.Med.Chem.Lett.