CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Protein disulfide-isomerase

Enzyme Information

5.3.4.1
Protein disulfide-isomerase.
based on mapping to UniProt P07237
Catalyzes the rearrangement of -S-S- bonds in proteins.
-!- Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.

UniProtKB Entries (1)

P07237
PDIA1_HUMAN
Homo sapiens
Protein disulfide-isomerase

PDB Structure

PDB 4EL1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insights into the redox-regulated dynamic conformations of human protein disulfide isomerase
Wang, C., Li, W., Ren, J., Fang, J., Ke, H., Gong, W., Feng, W., Wang, C.-C.
Antioxid Redox Signal