CATH Domain 4ea5A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.340	Endonuclease III; domain 1
	1.10.340.30	Hypothetical protein; domain 2

Domain Context

CATH Clusters

Superfamily	Hypothetical protein; domain 2
Functional Family	Methyl-CpG-binding domain protein 4

Enzyme Information

3.2.2.-

Hydrolyzing N-glycosyl compounds.

based on mapping to UniProt O95243

UniProtKB Entries (1)

MBD4_HUMAN

Homo sapiens

Methyl-CpG-binding domain protein 4

PDB Structure

PDB	4EA5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA. Morera, S., Grin, I., Vigouroux, A., Couve, S., Henriot, V., Saparbaev, M., Ishchenko, A.A. Nucleic Acids Res.