CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.1410.10
Functional Family Terminal uridylyltransferase cid1

Enzyme Information

2.7.7.19
Polynucleotide adenylyltransferase.
based on mapping to UniProt O13833
ATP + RNA(n) = diphosphate + RNA(n+1).
-!- Also acts slowly with CTP. -!- Catalyzes template-independent extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- The primer, depending on the source of the enzyme, may be an RNA or DNA fragment or oligo(A) bearing a 3'-OH terminal group. -!- See also EC 2.7.7.6.
2.7.7.52
RNA uridylyltransferase.
based on mapping to UniProt O13833
UTP + RNA(n) = diphosphate + RNA(n+1).
-!- Requires an oligoribonucleotide or polyribonucleotide with a free terminal 3'-OH as a primer.

UniProtKB Entries (1)

O13833
CID1_SCHPO
Schizosaccharomyces pombe 972h-
Terminal uridylyltransferase cid1

PDB Structure

PDB 4E8F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase.
Yates, L.A., Fleurdepine, S., Rissland, O.S., De Colibus, L., Harlos, K., Norbury, C.J., Gilbert, R.J.
Nat.Struct.Mol.Biol.