CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1270 | Substrate Binding Domain Of Dnak; Chain:A; Domain 2 |
|
1.20.1270.60 | Arfaptin homology (AH) domain/BAR domain |
Domain Context
CATH Clusters
| Superfamily | Arfaptin homology (AH) domain/BAR domain |
| Functional Family | Tyrosine-protein kinase |
Enzyme Information
| 2.7.10.2 |
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P07332
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.
|
UniProtKB Entries (1)
| P07332 |
FES_HUMAN
Homo sapiens
Tyrosine-protein kinase Fes/Fps
|
PDB Structure
| PDB | 4DYL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
F-BAR domain of human FES tyrosine kinase
TO BE PUBLISHED
|