CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.50.10
Functional Family

Enzyme Information

3.2.1.14
Chitinase.
based on mapping to UniProt B6A879
Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta- linkages in chitin and chitodextrins.
-!- The enzyme binds to chitin and randomly cleaves glycosidic linkages in chitin and chitodextrins in a non-processive mode, generating chitooligosaccharides and free ends on which exo-chitinases and exo- chitodextrinases can act. -!- Activity is greatly stimulated in the presence of EC 1.14.99.53, which attacks the crystalline structure of chitin and makes the polymer more accesible to the chitinase. -!- Cf. EC 3.2.1.202.

UniProtKB Entries (1)

B6A879
CHI2_YERET
Yersinia entomophaga
Chitinase 2

PDB Structure

PDB 4DWS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device.
Busby, J.N., Panjikar, S., Landsberg, M.J., Hurst, M.R., Lott, J.S.
Nature