CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q38087
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
3.1.11.-
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q38087

UniProtKB Entries (1)

Q38087
DPOL_BPR69
Enterobacteria phage RB69
DNA-directed DNA polymerase

PDB Structure

PDB 4DTP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA.
Xia, S., Vashishtha, A., Bulkley, D., Eom, S.H., Wang, J., Konigsberg, W.H.
Biochemistry