CATH Domain 4druB01

Superfamily
Functional Family	-

PDB	4DRU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties. Cummings, M.D., Lin, T.I., Hu, L., Tahri, A., McGowan, D., Amssoms, K., Last, S., Devogelaere, B., Rouan, M.C., Vijgen, L., Berke, J.M., Dehertogh, P., Fransen, E., Cleiren, E., van der Helm, L., Fanning, G., Van Emelen, K., Nyanguile, O., Simmen, K., Raboisson, P., Vendeville, S. Angew.Chem.Int.Ed.Engl.