CATH Classification
| Level | CATH Code | Description | 
|---|---|---|
|   | 1 | Mainly Alpha | 
|   | 1.20 | Up-down Bundle | 
|   | 1.20.190 | Delta-Endotoxin; domain 1 | 
|   | 1.20.190.20 | 14-3-3 domain | 
Domain Context
CATH Clusters
| Superfamily | 14-3-3 domain | 
| Functional Family | 14-3-3 gamma 1 | 
Enzyme Information
UniProtKB Entries (1)
| P31947 | 1433S_HUMAN Homo sapiens 14-3-3 protein sigma | 
PDB Structure
| PDB | 4DHS | 
| External Links | |
| Method | X-RAY DIFFRACTION | 
| Organism | |
| Primary Citation | Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.) | 
