CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.9
Enteropeptidase.
based on mapping to UniProt P98073
Activation of trypsinogen by selective cleavage of 6-Lys-|-Ile-7 bond.
-!- Activates trypsinogen. -!- Not inhibited by protein inhibitors of trypsin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.8.

UniProtKB Entries (1)

P98073
ENTK_HUMAN
Homo sapiens
Enteropeptidase

PDB Structure

PDB 4DGJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a supercharged variant of the human enteropeptidase light chain.
Simeonov, P., Zahn, M., Strater, N., Zuchner, T.
Proteins