CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.128 | Lipocalin |
|
2.40.128.90 | OMPT-like |
Domain Context
CATH Clusters
| Superfamily | OMPT-like |
| Functional Family |
Enzyme Information
| 3.4.23.48 |
Plasminogen activator Pla.
based on mapping to UniProt P17811
Converts human Glu-plasminogen to plasmin by cleaving the 560-Arg-|-Val- 561 peptide bond that is also hydrolyzed by the mammalian u-plasminogen activator and t-plasminogen activator. Also cleaves arginyl bonds in other proteins.
-!- From the bacterium Yersinia pestis that causes plague. -!- Belongs to peptidase family A26.
|
UniProtKB Entries (2)
| P00747 |
PLMN_HUMAN
Homo sapiens
Plasminogen
|
| P17811 |
COLY_YERPE
Yersinia pestis
Coagulase/fibrinolysin
|
PDB Structure
| PDB | 4DCB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for activation of an integral membrane protease by lipopolysaccharide.
J.Biol.Chem.
|