CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family

Enzyme Information

2.4.2.1
Purine-nucleoside phosphorylase.
based on mapping to UniProt O34925
(1) Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. (2) Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.
-!- Specificity not completely determined. -!- Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5.

UniProtKB Entries (1)

O34925
DEOD_BACSU
Bacillus subtilis subsp. subtilis str. 168
Purine nucleoside phosphorylase DeoD-type

PDB Structure

PDB 4DA0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases.
de Giuseppe, P.O., Martins, N.H., Meza, A.N., Dos Santos, C.R., Pereira, H.D., Murakami, M.T.
Plos One