CATH Classification

Domain Context

CATH Clusters

Superfamily TPP-binding domain
Functional Family

Enzyme Information

3.7.1.11
Cyclohexane-1,2-dione hydrolase.
based on mapping to UniProt P0CH62
Cyclohexane-1,2-dione + H(2)O = 6-oxohexanoate.
-!- Highly specific; does not act on cyclohexanone or cyclohexane-1,3- dione as substrate.

UniProtKB Entries (1)

P0CH62
CHDH_AZOSP
Azoarcus sp.
Cyclohexane-1,2-dione hydrolase

PDB Structure

PDB 4D5G
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Extended Reaction Scope of Thiamine Diphosphate Dependent Cyclohexane-1,2-Dione Hydrolase: From C-C Bond Cleavage to C-C Bond Ligation.
Loschonsky, S., Wacker, T., Waltzer, S., Giovannini, P.P., Mcleish, M.J., Andrade, S.L.A., Muller, M.
Angew.Chem.Int.Ed.Engl.