CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family 3-phosphoinositide-dependent protein kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O15530
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O15530
PDPK1_HUMAN
Homo sapiens
3-phosphoinositide-dependent protein kinase 1

PDB Structure

PDB 4CT1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular Mechanism of Regulation of the Atypical Protein Kinase C by N-Terminal Domains and an Allosteric Small Compound.
Zhang, H., Neimanis, S., Lopez-Garcia, L.A., Arencibia, J.M., Amon, S., Stroba, A., Zeuzem, S., Proschak, E., Stark, H., Bauer, A.F., Busschots, K., Jorgensen, T.J., Engel, M., Schulze, J.O., Biondi, R.M.
Chem.Biol.