1 keywords

CATH Domain 4cqfA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.800 Arginase; Chain A
Homologous Superfamily 3.40.800.20 Histone deacetylase domain

Domain Context

CATH Clusters

Superfamily Histone deacetylase domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

A5H660
A5H660_SCHMA
Schistosoma mansoni
Histone deacetylase 8

PDB Structure

PDB 4CQF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular Basis for the Anti-Parasitic Activity of a Mercaptoacetamide Derivative that Inhibits Histone Deacetylase 8 (Hdac8) from the Human Pathogen Schistosoma Mansoni
Stolfa, D.A., Marek, M., Lancelot, J., Hauser, A.T., Walter, A., Leproult, E., Melesina, J., Rumpf, T., Wurtz, J.M., Cavarelli, J., Sippl, W., Pierce, R.J., Romier, C., Jung, M.
J.Mol.Biol.