CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.559 | Chloramphenicol Acetyltransferase |
|
3.30.559.10 | Chloramphenicol acetyltransferase-like domain |
Domain Context
CATH Clusters
| Superfamily | Chloramphenicol acetyltransferase-like domain |
| Functional Family |
Enzyme Information
| 2.3.1.28 |
Chloramphenicol O-acetyltransferase.
based on mapping to UniProt P00484
Acetyl-CoA + chloramphenicol = CoA + chloramphenicol 3-acetate.
-!- Chloramphenicol is an antibiotic.
|
UniProtKB Entries (1)
| P00484 |
CAT3_ECOLX
Escherichia coli
Chloramphenicol acetyltransferase 3
|
PDB Structure
| PDB | 4CLA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Alternative binding modes for chloramphenicol and 1-substituted chloramphenicol analogues revealed by site-directed mutagenesis and X-ray crystallography of chloramphenicol acetyltransferase.
Biochemistry
|