×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Dehydroquinase, class II
Functional Family 3-dehydroquinate dehydratase

Enzyme Information

4.2.1.10
3-dehydroquinate dehydratase.
based on mapping to UniProt P9WPX7
3-dehydroquinate = 3-dehydroshikimate + H(2)O.

UniProtKB Entries (1)

P9WPX7
AROQ_MYCTU
Mycobacterium tuberculosis H37Rv
3-dehydroquinate dehydratase

PDB Structure

PDB 4CIW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Exploring the water-binding pocket of the type II dehydroquinase enzyme in the structure-based design of inhibitors.
Blanco, B., Sedes, A., Peon, A., Otero, J.M., van Raaij, M.J., Thompson, P., Hawkins, A.R., Gonzalez-Bello, C.
J. Med. Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...