CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.360
Functional Family

Enzyme Information

1.5.1.38
FMN reductase (NADPH).
based on mapping to UniProt Q88J85
FMNH(2) + NADP(+) = FMN + NADPH.
-!- The enzymes from bioluminescent bacteria contain FMN, while the enzyme from Escherichia coli does not. -!- The enzyme often forms a two-component system with monooxygenases such as luciferase. -!- Unlike EC 1.5.1.39, this enzyme does not use NADH as acceptor. -!- While FMN is the preferred substrate, the enzyme can also use FAD and riboflavin with lower activity. -!- Formerly EC 1.5.1.29 and EC 1.6.8.1.

UniProtKB Entries (1)

Q88J85
MSUE_PSEPK
Pseudomonas putida KT2440
FMN reductase (NADPH)

PDB Structure

PDB 4C76
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Fmn-Reductase Msue from Pseudomonas Putida Kt2440.
Gibson, R.P., Isupov, M., Littlechild, J.A.
To be Published